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Depending on the individual, different results may be achieved

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Brain-derived neurotrophic factor serum levels and genotype: association with depression during interferon-alpha treatment

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However, these patients had multiple risk factors for b12 deficiency beyond semaglutide use, including previous gastric surgery that permanently alters stomach anatomy and reduces intrinsic factor production

Frequency Based on Severity : Mild deficiency : Injections may be needed every 3-6 months